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4180

Joseph Reth

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Joseph Reth
CEO & Co-Founder of
Autopoiesis Sciences (2025)
About

Joseph Reth is the Co-Founder and CEO of Autopoiesis Sciences, a San Francisco-based AI research lab building autonomous scientific superintelligence to accelerate breakthrough discoveries across all scientific domains.

Before founding

A self-taught programmer since age 9, Reth attended Modesto Junior College for Computer Science at 14 and briefly studied at San Francisco State University before dropping out to pursue entrepreneurship.

Founder Insights

Reth previously served as founding CEO of Lossless Research, a pioneering AI lab dedicated to conscious artificial intelligence, where he contracted with DARPA and the U.S. Army Research Laboratory (DEVCOM ARL).

Experience

At 16, Reth founded RethDigital, one of the fastest-growing digital agencies in the U.S., building the world's first AI social media marketer for brands like HBO, National Geographic, and Target long before ChatGPT.

Scale & Impact

Autopoiesis Sciences raised $11M in seed funding led by Threshold Ventures, and its AI co-scientist model, Aristotle, is trusted by researchers at institutions including GSK, Pfizer, Stanford, MIT, Harvard, and the FDA.

4180

Joseph Reth

Autopoiesis Sciences
CEO
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Joseph Reth

Company(s)

Autopoiesis Sciences

Industry

Healthtech & Biotech

Year Founded

2025

Stage/Funding

Seed • $11M

Company Location

us

Connect

About

Joseph Reth is the Co-Founder and CEO of Autopoiesis Sciences, a San Francisco-based AI research lab building autonomous scientific superintelligence to accelerate breakthrough discoveries across all scientific domains.

Before founding

A self-taught programmer since age 9, Reth attended Modesto Junior College for Computer Science at 14 and briefly studied at San Francisco State University before dropping out to pursue entrepreneurship.

Founder Insights

Reth previously served as founding CEO of Lossless Research, a pioneering AI lab dedicated to conscious artificial intelligence, where he contracted with DARPA and the U.S. Army Research Laboratory (DEVCOM ARL).

Experience

At 16, Reth founded RethDigital, one of the fastest-growing digital agencies in the U.S., building the world's first AI social media marketer for brands like HBO, National Geographic, and Target long before ChatGPT.

Scale & Impact

Autopoiesis Sciences raised $11M in seed funding led by Threshold Ventures, and its AI co-scientist model, Aristotle, is trusted by researchers at institutions including GSK, Pfizer, Stanford, MIT, Harvard, and the FDA.

About

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