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2136

Prof. Nathalie Chaput-Gras

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Prof. Nathalie Chaput-Gras
CEO & Co-Founder of
Signadori Bio (2025)
About

Prof. Nathalie Chaput-Gras is Co-Founder of Signadori Bio, a Paris-based preclinical biopharmaceutical company pioneering next-generation, off-the-shelf monocyte immunotherapy for solid tumours.

Before founding

She serves as Professor and Lab Head of the Laboratory for Immunomonitoring in Oncology (LIO) at Gustave Roussy, Europe's leading cancer centre, and is affiliated with the University Paris-Saclay School of Pharmacy.

Founder Insights

A world-renowned immuno-oncologist, she holds an Immunology D-index of 68 with over 29,000 citations and received the 2025 Research.com Immunology in France Leader Award.

Experience

She co-founded Signadori Bio in 2025 alongside Dr. Jean-Luc Perfettini, translating groundbreaking Gustave Roussy research on p21-driven monocyte reprogramming into a clinical-stage pipeline backed by Sofinnova Partners, Invivo Partners, and Taiho Ventures.

Scale & Impact

Signadori Bio has raised EUR 11.1 million in seed financing and is advancing lead programme SiB-2101 toward lead candidate nomination, targeting unmet needs in solid tumour treatment.

2136

Prof. Nathalie Chaput-Gras

Signadori Bio
Co-Founder
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Prof. Nathalie Chaput-Gras

Company(s)

Signadori Bio

Industry

Healthtech & Biotech

Year Founded

2025

Stage/Funding

Seed • $11.1M

Company Location

fr

Connect

About

Prof. Nathalie Chaput-Gras is Co-Founder of Signadori Bio, a Paris-based preclinical biopharmaceutical company pioneering next-generation, off-the-shelf monocyte immunotherapy for solid tumours.

Before founding

She serves as Professor and Lab Head of the Laboratory for Immunomonitoring in Oncology (LIO) at Gustave Roussy, Europe's leading cancer centre, and is affiliated with the University Paris-Saclay School of Pharmacy.

Founder Insights

A world-renowned immuno-oncologist, she holds an Immunology D-index of 68 with over 29,000 citations and received the 2025 Research.com Immunology in France Leader Award.

Experience

She co-founded Signadori Bio in 2025 alongside Dr. Jean-Luc Perfettini, translating groundbreaking Gustave Roussy research on p21-driven monocyte reprogramming into a clinical-stage pipeline backed by Sofinnova Partners, Invivo Partners, and Taiho Ventures.

Scale & Impact

Signadori Bio has raised EUR 11.1 million in seed financing and is advancing lead programme SiB-2101 toward lead candidate nomination, targeting unmet needs in solid tumour treatment.

About

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